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Type: Artigo
Title: The fatty acid synthase inhibitor orlistat reduces the growth and metastasis of orthotopic tongue oral squamous cell carcinomas
Author: Agostini, M.
Almeida, L.Y.
Bastos, D.C.
Ortega, R.M.
Moreira, F.S.
Seguin, F.
Zecchin, K.G.
Raposo, H.F.
Oliveira, H.C.F.
Amoedo, N.D.
Salo, T.
Coletta, R.D.
Graner, E.
Abstract: Fatty acid synthase (FASN) is the biosynthetic enzyme responsible for the endogenous synthesis of fatty acids. It is downregulated in most normal cells, except in lipogenic tissues such as liver, lactating breast, fetal lung, and adipose tissue. Conversel
Subject: Carcinoma de células escamosas
Country: Estados Unidos
Editor: American Association for Cancer Research
Citation: Molecular Cancer Therapeutics. American Association For Cancer Research Inc., v. 13, n. 3, p. 585 - 595, 2014.
Rights: Fechado
Identifier DOI: 10.1158/1535-7163.MCT-12-1136
Date Issue: 2014
Appears in Collections:IB - Artigos e Outros Documentos
FOP - Artigos e Outros Documentos

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