Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/86331
Full metadata record
DC FieldValueLanguage
dc.contributor.CRUESPUNIVERSIDADE DE ESTADUAL DE CAMPINASpt_BR
dc.typeArtigo de periódicopt_BR
dc.titlePituitary Macroadenoma Presenting As A Nasal Tumor: Case Report [macroadenoma Hipofisário, Apresentando-se Como Um Tumor Nasal: Relato De Caso]pt_BR
dc.contributor.authorSilva N.A.pt_BR
dc.contributor.authorReis F.pt_BR
dc.contributor.authorMiura L.K.pt_BR
dc.contributor.authorVieira G.H.pt_BR
dc.contributor.authorQueiroz L.S.pt_BR
dc.contributor.authorGarmes H.M.pt_BR
dc.contributor.authorBenetti-Pinto C.L.pt_BR
unicamp.authorSilva, N.A., Jr., Department of Radiology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazil, Departments of Radiology, Pathology, Endocrinology and Gynecology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazilpt_BR
unicamp.authorReis, F., Department of Radiology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazil, Departments of Radiology, Pathology, Endocrinology and Gynecology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazilpt_BR
unicamp.authorMiura, L.K., Department of Radiology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazil, Departments of Radiology, Pathology, Endocrinology and Gynecology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazilpt_BR
unicamp.authorVieira, G.H., Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazil, Departments of Radiology, Pathology, Endocrinology and Gynecology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazilpt_BR
unicamp.authorQueiroz, L.S., Department of Pathology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazil, Departments of Radiology, Pathology, Endocrinology and Gynecology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazilpt_BR
unicamp.authorGarmes, H.M., Department of Endocrinology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazil, Departments of Radiology, Pathology, Endocrinology and Gynecology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazilpt_BR
unicamp.authorBenetti-Pinto, C.L., Department of Obstetrics and Gynecology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazil, Departments of Radiology, Pathology, Endocrinology and Gynecology, Universidade Estadual de Campinas (Unicamp)Campinas, São Paulo, Brazilpt_BR
dc.description.abstractCONTEXT: Pituitary macroadenomas are rare intracranial tumors. In a few cases, they may present aggressive behavior and invade the sphenoid sinus and nasal cavity, causing unusual symptoms. In this paper, we report an atypical case of pituitary adenoma presenting as a nasal mass.CASE REPORT: The patient was a 44-year-old woman who had had amenorrhea and galactorrhea for ten months, with associated nasal obstruction, macroglossia and acromegaly. Both growth hormone and prolactin levels were increased. Magnetic resonance imaging showed a large mass originating from the lower surface of the pituitary gland, associated with sella turcica erosion and tumor extension through the sphenoid sinus and nasal cavity. Histopathological analysis demonstrated a chromophobe pituitary adenoma with densely packed rounded epithelial cells, with some atypias and rare mitotic figures. There was no evidence of metastases.CONCLUSION: Macroadenoma invading the nasal cavity is a rare condition and few similar cases have been reported in the literature. This study contributes towards showing that tumor extension to the sphenoid sinus and nasopharynx needs to be considered and investigated in order to make an early diagnosis when atypical symptoms like nasal obstruction are present.en
dc.relation.ispartofSao Paulo Medical Journalpt_BR
dc.publisherAssociacao Paulista de Medicinapt_BR
dc.date.issued2014pt_BR
dc.identifier.citationSao Paulo Medical Journal. Associacao Paulista De Medicina, v. 132, n. 6, p. 373 - 377, 2014.pt_BR
dc.language.isoenpt_BR
dc.description.volume132pt_BR
dc.description.issuenumber6pt_BR
dc.description.firstpage373pt_BR
dc.description.lastpage377pt_BR
dc.rightsabertopt_BR
dc.sourceScopuspt_BR
dc.identifier.issn15163180pt_BR
dc.identifier.doi10.1590/1516-3180.2014.1326693pt_BR
dc.identifier.urlhttp://www.scopus.com/inward/record.url?eid=2-s2.0-84908265878&partnerID=40&md5=403328b9f70b816a75da8441cab30505pt_BR
dc.date.available2015-06-25T17:52:45Z
dc.date.available2015-11-26T14:19:16Z-
dc.date.accessioned2015-06-25T17:52:45Z
dc.date.accessioned2015-11-26T14:19:16Z-
dc.description.provenanceMade available in DSpace on 2015-06-25T17:52:45Z (GMT). No. of bitstreams: 1 2-s2.0-84908265878.pdf: 1580340 bytes, checksum: b84beab965886584d7ca23b74d602b8e (MD5) Previous issue date: 2014en
dc.description.provenanceMade available in DSpace on 2015-11-26T14:19:16Z (GMT). No. of bitstreams: 2 2-s2.0-84908265878.pdf: 1580340 bytes, checksum: b84beab965886584d7ca23b74d602b8e (MD5) 2-s2.0-84908265878.pdf.txt: 20029 bytes, checksum: d413b190add10d145dbbcf097a6e4c5b (MD5) Previous issue date: 2014en
dc.identifier.urihttp://www.repositorio.unicamp.br/handle/REPOSIP/86331
dc.identifier.urihttp://repositorio.unicamp.br/jspui/handle/REPOSIP/86331-
dc.identifier.idScopus2-s2.0-84908265878pt_BR
dc.description.referenceCole, I.E., Keene, M., Nasal obstruction in pituitary tumours (1981) J Laryngol Otol, 95 (2), pp. 183-189pt_BR
dc.description.referenceDaita, G., Makino, K., Goto, S., Ueno, K., Takamura, H., Nasopharyngeal extension of a large chromophobe adenoma of the pituitary (author’s transl) (1976) No Shinkei Geka, 4 (7), pp. 699-706pt_BR
dc.description.referenceCook, R.J., Besser, M., A 16 year old boy with poor vision and nasal obstruction (1987) Aust N Z J Surg, 57 (7), pp. 485-488pt_BR
dc.description.referenceLuk, I.S., Chan, J.K., Chow, S.M., Leung, S., Pituitary adenoma presenting as sinonasal tumor: Pitfalls in diagnosis (1996) Hum Pathol, 27 (6), pp. 605-609pt_BR
dc.description.referenceBeriat, G.K., Doğan, C., Akmansu, S.H., Karadağ, D., Doğan, H., A rare cause of nasal obstruction: Giant invasive nonfunctioning pituitary adenoma (2010) Kulak Burun Bogaz Ihtis Derg, 20 (6), pp. 309-313pt_BR
dc.description.referenceGodey, B., Morandi, X., Le Gall, F., Pituitary adenomas with infra-sellar extension into the nasopharynx (1999) J Laryngol Otol, 113 (12), pp. 1109-1111pt_BR
dc.description.referenceDent, J.A., Rickhuss, P.K., Invasive pituitary adenoma presenting with nasal obstruction (1989) J Laryngol Otol, 103 (6), pp. 605-609pt_BR
dc.description.referenceSummers, G.W., Nasal obstruction caused by a pituitary chromophobe adenoma (1976) Laryngoscope, 86 (11), pp. 1718-1721pt_BR
dc.description.referenceInagawa, H., Ishizawa, K., Mitsuhashi, T., Giant invasive pituitary adenoma extending into the sphenoid sinus and nasopharynx: Report of a case with intraoperative cytologic diagnosis (2005) Acta Cytol, 49 (4), pp. 452-456pt_BR
dc.description.referenceMargo, C.E., Gonzalvo, A.A., Extracranial manifestation of invasive pituitary adenoma (1987) South Med J, 80 (3), pp. 381-383pt_BR
dc.description.referenceJankiewicz-Wika, J., Pawlikowski, M., Zawirski, M., Stepień, H., [Pituitary adenoma penetrating the sphenoidal sinus and nasal cavity: A case report] (2001) Neurol Neurochir Pol, 35 (4), pp. 727-732pt_BR
dc.description.referenceKaltsas, G.A., Nomikos, P., Kontogeorgos, G., Buchfelder, M., Grossman, A.B., Clinical review: Diagnosis and management of pituitary carcinomas (2005) J Clin Endocrinol Metab, 90 (5), pp. 3089-3099pt_BR
dc.description.referenceKikuchi, K., Kowada, M., Sasaki, J., Sageshima, M., Large pituitary adenoma of the sphenoid sinus and the nasopharynx: Report of a case with ultrastructural evaluations (1994) Surg Neurol, 42 (4), pp. 330-334pt_BR
dc.description.referenceDavis, P.C., Hoffman, J.C., Jr., Spencer, T., Tindall, G.T., Braun, I., Imaging of pituitary adenoma: CT, clinical, and surgical correlation (1987) AJR am J Roentgenol, 148 (4), pp. 797-802pt_BR
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
2-s2.0-84908265878.pdf1.54 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.