Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/86280
Type: Artigo de periódico
Title: Evaluation Of The Cytotoxicity And Phototoxicity Of Caryocar Brasiliense Supercritical Carbon Dioxide Extract
Author: Amaral L.F.B.
Moriel P.
Foglio M.A.
Mazzola P.G.
Abstract: Background: Caryocar brasiliense Camb (Pequi) is a typical Brazilian Cerrado fruit tree. Its fruit is used as a vitamin source for culinary purposes and as a source of oil for the manufacture of cosmetics. C. brasiliense supercritical CO2 extracts exhibit antimicrobial activity against the bacteria Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus and also possess antioxidant activity. This study was designed to evaluate the in vitro cytotoxicity and phototoxicity of the supercritical CO2 extract obtained from the leaves of this species. Methods: In vitro cytotoxicity and phototoxicity of C. brasiliense supercritical CO2 extracts were assessed using a tetrazolium-based colorimetric assay (XTT) and Neutral Red methods. Results: We found that the C. brasiliense (Pequi) extract obtained by supercritical CO2 extraction did not present cytotoxic and phototoxic hazards. Conclusions: This finding suggests that the extract may be useful for the development of cosmetic and/or pharmaceutical products.
Editor: BioMed Central Ltd.
Rights: aberto
Identifier DOI: 10.1186/1472-6882-14-450
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-84924288100&partnerID=40&md5=054d38accfcf56439fc899ce372f58db
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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