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Type: Artigo de periódico
Title: The Seasonality Of Respiratory Viruses In Patients With Chronic Rhinosinusitis
Author: Lima J.T.
Paula F.E.
Proenca-Modena J.L.
Demarco R.C.
Buzatto G.P.
Saturno T.H.
Delcaro L.S.
Tamashiro E.
Valera F.C.P.
Arruda E.
Anselmo-Lima W.T.
Abstract: Background: Chronic rhinosinusitis (CRS) is a common illness, yet little is known about its pathogenesis, including the role played by respiratory viruses. Methods: A transversal prospective study was conducted to analyze the seasonality of CRS using real-time polymerase chain reaction to detect respiratory virus genomes in secretions and tissue samples from patients with CRS with and without nasal polyps. Results: The frequency of viral detection was 41% (31/75). The respiratory virus most frequently detected was human rhinovirus, found in 18 patients (24%), followed by human metapneumovirus, human enterovirus, human respiratory sincicial virus, human adenovirus, human bocavirus, human coronavirus, and human influenza virus, detected in 12 (16%), five (6.6%), four (5.3%), four (5.3%), two (2.6%), two (2.6%), and one (1.3%) patient(s), respectively. Although none of the patients presented symptoms when the samples were collected, there was a peak in detection of the most prevalent virus in the autumn and winter seasons of both years, similar to the pattern that occurs in acute conditions. Conclusions: The pattern of respiratory virus seasonality found in nasal mucosa, polyps, and paranasal sinus samples in patients with CRS reinforces the possibility of asymptomatic respiratory viral infections.
Editor: OceanSide Publications Inc.
Rights: fechado
Identifier DOI: 10.2500/ajra.2015.29.4129
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

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