Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/85343
Type: Artigo de periódico
Title: Polycystic Ovary Syndrome And Chronic Autoimmune Thyroiditis
Author: De Souza Mayrink Novais J.
Benetti-Pinto C.L.
Garmes H.M.
Jales R.M.
Juliato C.R.T.
Abstract: Introduction: Polycystic ovary syndrome (PCOS) has been associated with an autoimmune origin, either per se or favoring the onset of autoimmune diseases, from a stimulatory action on the inflammatory response. Thus, autoimmune thyroiditis (AIT) could be more prevalent among women with PCOS. Objective: To evaluate the prevalence of AIT in women with PCOS. Study design: It was a cross-sectional study, in a tertiary center, including 65 women with PCOS and 65 women without this condition. Clinical and laboratory parameters were evaluated and a thyroid ultrasound scan was performed. Levels of thyroid-stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), anti-thyroid peroxidase (anti-TPO) antibodies, anti-thyroglobulin (anti-TG) antibodies, and thyroid ultrasound findings were evaluated. Results: The prevalence of subclinical hypothyroidism (SCH) in women with PCOS was 16.9% and 6.2% in the non-PCOS group. AIT was more common in the PCOS group compared with the non-PCOS group (43.1% versus 26.2%). But, when it was adjusted by weight and insulin resistance, the difference in the thyroiditis risk was not observed (OR 0.78, CI 0.28-2.16). Conclusion: AIT risk was similar in the PCOS and the non-PCOS group. SCH are more common in women with PCOS, highlighting a need for periodic monitoring of thyroid function.
Editor: Informa Healthcare
Rights: fechado
Identifier DOI: 10.3109/09513590.2014.958990
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-84917710503&partnerID=40&md5=561cd912515b0bcb29947f678d78721d
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

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