Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/85297
Type: Artigo de periódico
Title: Effect Of Low-level Laser Therapy (lllt) On Peripheral Nerve Regeneration Using Fibrin Glue Derived From Snake Venom
Author: Buchaim R.L.
Andreo J.C.
Barraviera B.
Ferreira Junior R.S.
Buchaim D.V.
Rosa Junior G.M.
de Oliveira A.L.R.
de Castro Rodrigues A.
Abstract: Objectives: The purpose of this study was to assess whether the adhesive permits the collateral repair of axons originating from a vagus nerve to the interior of a sural nerve graft, and whether low-level laser therapy (LLLT) assists in the regeneration process. Materials and methods: Study sample consisted of 32 rats randomly separated into three groups: Control Group (CG; n = 8), from which the intact sural nerve was collected; Experimental Group (EG; n = 12), in which one of the ends of the sural nerve graft was coapted to the vagus nerve using the fibrin glue; and Experimental Group Laser (EGL; n = 12), in which the animals underwent the same procedures as those in EG with the addition of LLLT. Ten weeks after surgery, the animals were euthanized. Morphological analysis by means of optical and electron microscopy, and morphometry of the regenerated fibers were employed to evaluate the results. Results: Collateral regeneration of axons was observed from the vagus nerve to the interior of the autologous graft in EG and EGL, and in CG all dimensions measured were greater and presented a significant difference in relation to EG and EGL, except for the area and thickness of the myelin sheath, that showed significant difference only in relation to the EG. Conclusions: The present study demonstrated that the fibrin glue makes axonal regeneration feasible and is an efficient method to recover injured peripheral nerves, and the use of low-level laser therapy enhances nerve regeneration.
Editor: Elsevier Ltd
Rights: fechado
Identifier DOI: 10.1016/j.injury.2015.01.031
Address: http://www.scopus.com/inward/record.url?eid=2-s2.0-84922223307&partnerID=40&md5=6c1ba3e7f6185b1d8fe905013ce5a8eb
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
2-s2.0-84922223307.pdf1.98 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.