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Type: Artigo de periódico
Title: Bispectral Index In Calves Anesthetized With Xylazine, Midazolam, Ketamine, Isoflurane And Subjected To Continuous Rate Infusion Of Lidocaine
Author: de Araujo M.A.
Beloti C.A.C.
Deschk M.
Arruda A.M.M.
Cheng L.S.
de Albuquerque V.B.
dos Santos P.S.P.
Abstract: PURPOSE: To assess the bispectral index (BIS) and recovery in calves anesthetized with xylazine, midazolam, ketamine and isoflurane and subjected to CRI of lidocaine. METHODS: Xilazine was administered followed by ketamine and midazolam, orotracheal intubation and maintenance on isoflurane using mechanical ventilation. Lidocaine (2 mg kg-1 bolus) or saline (0.9%) was administered IV followed by a CRI (100 μg kg-1 minute-1) of lidocaine (L) or saline (C). Were recorded BIS, heart rate (HR), mean arterial pressure (MAP) and rectal temperature (RT) before administration of premedication (TB) and 15 minutes after (TX), before administering lidocaine (T0) and 20, 40, 60 and 80 minutes after the start of the CRI. Time do sternal recumbency (SRE) and standing (ST) and plasma lidocaine concentration also evaluated. RESULTS: In both treatments BIS decreased significantly at all times compared to TB. TX was higher than the subsequent times. HR decreased from baseline at all times and decreased from T40 in L compared to C. SRE was higher in L compared to C. CONCLUSIONS: Bispectral index values were consistent with the degree of hypnosis of the animals. Lidocaine did not potentiate isoflurane anesthesia assessed by BIS in unstimulated calves anesthetized with constant E´Iso. Lidocaine increased the time to sternal recumbency.
Editor: Sociedade Brasileira para o Desenvolvimento de Pesquisa em Cirurgia
Rights: aberto
Identifier DOI: 0.1590/S0102-86502015001000009
Date Issue: 2015
Appears in Collections:Unicamp - Artigos e Outros Documentos

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