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Type: Patente
Title: 4-anilinochinazolin Derivate Mit Adenosinkinase Hemmenden Eigenschaften
Author: Gomes Franchini Kleber [br]
Abdalla Saad Mario [br]
Rittner Neto Roberto [br]
Marin Rodrigo [br]
Rocco Aparecida Silvana [br]
Abstract: The present invention relates to the use of 4-anilinoquinazoline derivatives as adenosine-kinase inhibitors. The present invention al so relates to a method for protecting tissues and organs like heart, brain and kidneys affected by ischemia, and for treating heart insufficiency, myocardium infarct, arrhythmia, arterial hypertension , atherosclerosis, coronary artery restenosis after angioplasty, chronic renal insufficiency, cerebral vascular accident, and chronic inflammatory diseases (e.g. rheumatoid arthritis). The present invention also relates to the compound 6,7 dimethoxy- 4- (3'-N',N'-dimethylaminoanilino) quinazoline, or a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising it and use of such compound in the manufacture of a medicament for treating or preventing diseases or conditions which are benefited from the adenosine kinase inhibition.
Rights: aberto
Date Issue: 15-Dec-2011
Appears in Collections:Patentes

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