Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/81961
Type: Artigo de periódico
Title: New prenylated metabolites of Deguelia longeracemosa and evaluation of their antimicrobial potential
Author: Magalhaes, AF
Tozzi, AMGA
Magalhaes, EG
Souza-Neta, LC
Abstract: The analysis of root extracts from Deguelia longeracemosa (Benth.) A.M.G. Azevedo yielded fifteen prenylated metabolites. Nine of them are novel, and their molecular structures were determined through spectral analyses (UV, IR, MS and NMR) as being five derivatives of 4-hydroxy-3-phenylcoumarin: 4-hydroxy-3-(4'-hydroxyphenyl)-5-methoxy-6-(8',9'-epoxy-9'-methyl-butyl)-2',2'-dimethylpyrano-(5',6':8,7)-coumarin; 4-hydroxy-3-(3',4'-methylenedioxyphenyl)-5-methoxy-6-(3,3-dimethylal-lyl)-2',2'-dimethypyrano-(5',6':8,7)-coumarin; 4-hydroxy-3-(3'-hydroxy-4'-methoxyphenyl)-5-methoxy-6-(3,3-dimethylal-lyl)-2',2'-dimethylpyrano-(5',6':8,7)-coumarin; 4-hydroxy-3(3'-hydroxy-4'-methoxyphenyl)-5-methoxy-2',2'-dimethylpyrano-(5',6':6,7)-coumarin and 4-hydroxy-3-[4'-O-(3,3-dimethylallyl)phenyl]-5-methoxy-2',2'-dimethylpyrano-(5',6':6,7)-coumarin, three derivatives of 1,2-diphenyl-1,2-ethanodione (alpha-oxo-deoxybenzoin derivatives): 1-[6-hydroxy-2-methoxy-3-(3,3-dimethylallyl)-2',2'-dimethylpyrano-(5',6':5,4)-]-2-(4-hydroxyphenyl)-1,2-ethanedione; 1-[6-hydroxy-2-methoxy-2',2'-dimethylpyrano-(5',6':3,4)]-2-(4'-methoxyphenyl)-1,2-ethanedione; 1-[6-hydroxy-2-methoxy-2',2'-dimethylpyrano-(5',6':3,4)]-2-(3',4'-methylenedioxyphenyl)-1,2-ethanedione and one derivative of deoxybenzoin: 2,4-dimethoxy-6-hydroxy-2',2'-dimethylpyrano-(5',6':3,4)-deoxybenzoin. The antimicrobial activity of roots extracts and some isolated compounds was screened through bioautography against bacteria and fungi.
Subject: Deguelia longeracemosa
leguminosae-papilionoideae
4-hydroxy-3-phenylcoumarins
1,2-diphenyl-1,2-ethanediones
deoxybenzoin
bioautography
Country: Alemanha
Editor: Georg Thieme Verlag Kg
Rights: aberto
Identifier DOI: 10.1055/s-2005-916232
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOS000236670700012.pdf151.84 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.