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|Type:||Artigo de periódico|
|Title:||Economic Impact of a Rotavirus Vaccine in Brazil|
|Author:||CONSTENLA, Dagna O.|
LINHARES, Alexandre C.
RHEINGANS, Richard D.
ANTIL, Lynn R.
WALDMAN, Eliseu A.
SILVA, Luiz J. da
|Abstract:||The study was done to evaluate the cost-effectiveness of a national rotavirus vaccination programme in Brazilian children from the healthcare system perspective. A hypothetical annual birth-cohort was followed for a five-year period. Published and national administrative data were incorporated into a model to quantify the consequences of vaccination versus no vaccination. Main outcome measures included the reduction in disease burden, lives saved, and disability-adjusted life-years (DALYs) averted. A rotavirus vaccination programme in Brazil would prevent an estimated 1,804 deaths associated with gastroenteritis due to rotavirus, 91,127 hospitalizations, and 550,198 outpatient visits. Vaccination is likely to reduce 76% of the overall healthcare burden of rotavirus-associated gastroenteritis in Brazil. At a vaccine price of US$ 7-8 per dose, the cost-effectiveness ratio would be US$ 643 per DALY averted. Rotavirus vaccination can reduce the burden of gastroenteritis due to rotavirus at a reasonable cost-effectiveness ratio.|
|Subject:||Costs and cost analysis|
|Editor:||I C D D R B-CENTRE HEALTH POPULATION RESEARCH|
|Citation:||JOURNAL OF HEALTH, POPULATION AND NUTRITION, v.26, n.4, p.388-396, 2008|
|Appears in Collections:||FCM - Artigos e Outros Documentos|
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|art_CONSTENLA_Economic_Impact_of_a_Rotavirus_Vaccine_in_2008.pdf||published version||3.8 MB||Adobe PDF||View/Open|
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