Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/815
Type: Artigo de periódico
Title: Economic Impact of a Rotavirus Vaccine in Brazil
Author: CONSTENLA, Dagna O.
LINHARES, Alexandre C.
RHEINGANS, Richard D.
ANTIL, Lynn R.
WALDMAN, Eliseu A.
SILVA, Luiz J. da
Abstract: The study was done to evaluate the cost-effectiveness of a national rotavirus vaccination programme in Brazilian children from the healthcare system perspective. A hypothetical annual birth-cohort was followed for a five-year period. Published and national administrative data were incorporated into a model to quantify the consequences of vaccination versus no vaccination. Main outcome measures included the reduction in disease burden, lives saved, and disability-adjusted life-years (DALYs) averted. A rotavirus vaccination programme in Brazil would prevent an estimated 1,804 deaths associated with gastroenteritis due to rotavirus, 91,127 hospitalizations, and 550,198 outpatient visits. Vaccination is likely to reduce 76% of the overall healthcare burden of rotavirus-associated gastroenteritis in Brazil. At a vaccine price of US$ 7-8 per dose, the cost-effectiveness ratio would be US$ 643 per DALY averted. Rotavirus vaccination can reduce the burden of gastroenteritis due to rotavirus at a reasonable cost-effectiveness ratio.
Subject: Costs and cost analysis
Diarrhoea
Infantile
Gastroenteritis
Morbidity
Rotavirus
Rotavirus vaccines
Vaccination
Brazil
Country: Bangladesh
Editor: I C D D R B-CENTRE HEALTH POPULATION RESEARCH
Rights: fechado
Address: http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000261491300002&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000261491300002&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
Date Issue: 2008
Appears in Collections:FCM - Artigos e Outros Documentos

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