Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/80871
Type: Artigo de periódico
Title: Leucotrichoic acid, a novel sesquiterpene from Sinningia leucotricha (Gesneriaceae)
Author: Verdan, MH
Unemoto, LK
Faria, RT
Salvador, MJ
de Sa, EL
Barison, A
Stefanello, MEA
Abstract: Chemical investigation of Sinningia leucotricha (Gesneriaceae) resulted in the isolation of leucotrichoic acid, a sesquiterpene with a novel triquinane skeleton, and the known triterpenes hederagenin and 23-hydroxyursolic acid. The chemical structures of all compounds were elucidated through spectroscopic analysis (NMR and MS). The conformational stability of the new compound was analyzed by density theory functional methods. A possible biogenesis for the new compound is proposed. Leucotrichoic acid was inactive against a panel of human cancer cell lines. (C) 2013 Elsevier Ltd. All rights reserved.
Subject: Gesneriaceae
Sinningia
Sesquiterpene
Triquinane
NMR
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Rights: fechado
Identifier DOI: 10.1016/j.tetlet.2013.06.108
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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