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|Type:||Artigo de periódico|
|Title:||Influence of probe pressure on the diffuse correlation spectroscopy blood flow signal: extra-cerebral contributions|
|Abstract:||A pilot study explores relative contributions of extra-cerebral (scalp/skull) versus brain (cerebral) tissues to the blood flow index determined by diffuse correlation spectroscopy (DCS). Microvascular DCS flow measurements were made on the head during baseline and breath-holding/hyperventilation tasks, both with and without pressure. Baseline (resting) data enabled estimation of extra-cerebral flow signals and their pressure dependencies. A simple two-component model was used to derive baseline and activated cerebral blood flow (CBF) signals, and the DCS flow indices were also cross-correlated with concurrent Transcranial Doppler Ultrasound (TCD) blood velocity measurements. The study suggests new pressure-dependent experimental paradigms for elucidation of blood flow contributions from extra-cerebral and cerebral tissues. (C) 2013 Optical Society of America|
|Editor:||Optical Soc Amer|
|Citation:||Biomedical Optics Express. Optical Soc Amer, v. 4, n. 7, n. 978, n. 994, 2013.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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