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Type: Artigo de periódico
Title: Influence of glycemic control on Epstein-Bar and Cytomegalovirus infection in periodontal pocket of type 2 diabetic subjects
Author: Casarin, RCV
Duarte, PM
Santos, VR
Lima, JA
Gagnon, G
Casati, MZ
Goncalves, RB
Abstract: Objective: The aim of the present study was to evaluate the influence of glycemic control on the frequency of Epstein-Bar (EBV) and Cytomegalovirus (CMV) in periodontal pockets of type 2 diabetic subjects with chronic periodontitis. Design: Forty-six subjects presenting generalized chronic periodontitis and type 2 diabetes mellitus (DM) were selected for this study. Polymerase chain reaction (PCR) was used to determine the presence of EBV and CMV in shallow [Probing Depth (PD) <= 3 mm], moderate (PD = 4-6 mm) and deep (PD > 7 mm) pockets. HbAlc levels <= 7%, >7 to <10%, and >= 10% defined good, moderate and poor glycemic control, respectively. Results: Higher frequency of EBV was found in the shallow pockets of the subjects with poor glycemic control (p < 0.05; chi-square test). Moreover, EBV-free subjects presented moderate or good glycemic control. Glycemic control did not influence the frequency of CMV in all pocket categories. Conclusion: Poor glycemic control in type 2 diabetic subjects can increase the occurrence of EBV in shallow periodontal pockets. (C) 2010 Elsevier Ltd. All rights reserved.
Subject: Herpesviruses
Periodontal disease
Glycemic control
Diabetes mellitus
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Citation: Archives Of Oral Biology. Pergamon-elsevier Science Ltd, v. 55, n. 11, n. 902, n. 906, 2010.
Rights: fechado
Identifier DOI: 10.1016/j.archoralbio.2010.07.009
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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