Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/79899
Type: Artigo de periódico
Title: Efficacy and safety of flexible-dose oral sildenafil citrate (Viagra((R))) in the treatment of erectile dysfunction in Brazilian and Mexican men
Author: Glina, S
Bertero, E
Claro, J
Damiao, R
Faria, G
Fregonesi, A
Jaspersen, J
Mendoza, A
Mattos, D
Rocha, LC
Sotomayor, M
Teloken, C
Ureta, S
Zonana, E
Ugarte, F
Abstract: A 12-week, double-blind, placebo-controlled, multicenter study evaluated the efficacy and safety of flexible-dose sildenafil citrate (Viagra((R))) treatment (25, 50 or 100 mg) in Brazilian and Mexican men with erectile dysfunction (ED) of broad-spectrum etiology. Efficacy was assessed on the basis of responses to the 15-item International Index of Erectile Function (IIEF) questionnaire, completed at baseline and after 12 weeks of treatment. At end point, mean scores for all IIEF domains of sexual function (erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction) were significantly (P < 0.0001) higher in the sildenafil group (n = 109) than in the placebo group (n = 105). These findings confirm the significant increases in frequency of penetration and frequency of maintained erections reported previously. Sildenafil treatment was well tolerated. The most common adverse events were headache and flushing. In conclusion, sildenafil is a well-tolerated and effective treatment for ED of broad-spectrum etiology in Latin American men.
Subject: sildenafil
erectile dysfunction
impotence
penile erection
Country: Inglaterra
Editor: Nature Publishing Group
Rights: fechado
Identifier DOI: 10.1038/sj.ijir.3900895
Date Issue: 2002
Appears in Collections:Unicamp - Artigos e Outros Documentos

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