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Type: Artigo de periódico
Title: Effects of the Topical Application of Hydroalcoholic Leaf Extract of Oncidium flexuosum Sims. (Orchidaceae) and Microcurrent on the Healing of Wounds Surgically Induced in Wistar Rats
Author: de Gaspi, FOD
Foglio, MA
de Carvalho, JE
Santos, GMT
Testa, M
Passarini, JR
de Moraes, CP
Esquisatto, MAM
Mendonca, JS
Mendonca, FAS
Abstract: This study evaluated the wound healing activity of hydroalcoholic leaf extract of Oncidium flexuosum Sims. (Orchidaceae), an important native plant of Brazil, combined or not with microcurrent stimulation. Wistar rats were randomly divided into four groups of nine animals: control (C), topical application of the extract (OF), treated with a microcurrent (10 mu A/2 min) (MC), and topical application of the extract plus microcurrent (OF + MC). Tissue samples were obtained 2, 6, and 10 days after injury and submitted to structural and morphometric analysis. The simultaneous application of OF + MC was found to be highly effective in terms of the parameters analyzed (P < .05), with positive effects on the area of newly formed tissue, number of fibroblasts, number of newly formed blood vessels, and epithelial thickness. Morphometric data confirmed the structural findings. The O. flexuosum leaf extract contains active compounds that speed the healing process, especially when applied simultaneously with microcurrent stimulation.
Country: EUA
Editor: Hindawi Publishing Corporation
Citation: Evidence-based Complementary And Alternative Medicine. Hindawi Publishing Corporation, n. 1, n. 9, 2011.
Rights: aberto
Identifier DOI: 10.1155/2011/950347
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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