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Type: Artigo de periódico
Title: Synthesis of potentially bioactive PABA-related N-(aminoalkyl)lactamic amino acids and esters via selective SNAr reactions
Author: Goncalves, RS
Abdelnur, PV
Santos, VG
Simas, RC
Eberlin, MN
Magalhaes, A
Gonzalez, ERP
Abstract: Potentially bioactive N-(aminoalkyl)lactamic amino acids and esters were synthesized in satisfactory to good yields by SNAr reactions of aromatic acids with N-(3-aminopropyl)lactams followed by esterification with tertiary amino alcohols. The addition-elimination SNAr mechanism was confirmed by NMR and MS measurements.
Subject: PABA derivatives
Potential bio-activity
SNAr reaction
Country: EUA
Editor: Springer
Citation: Amino Acids. Springer, v. 40, n. 1, n. 197, n. 204, 2011.
Rights: fechado
Identifier DOI: 10.1007/s00726-010-0634-z
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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