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Type: Artigo de periódico
Title: Comparative clinicopathological study of intraoral sebaceous hyperplasia and sebaceous adenoma
Author: Azevedo, RS
Almeida, OP
Netto, JNS
Miranda, AMMA
Santos, TCRB
Della Coletta, R
Lopes, MA
Pires, FR
Abstract: Objective. The objective of this study was to compare the clinicopathological features of oral sebaceous hyperplasia and sebaceous adenoma. Study design. Clinical data, microscopical characteristics, and ki-67 immunoexpression were comparatively analyzed on 2 intraoral sebaceous adenomas, 6 intraoral sebaceous hyperplasias, and 21 normal intraoral sebaceous glands. Results. Clinically, sebaceous glands presented as multiple separated papules, sebaceous hyperplasias as a single enlarged papule, and sebaceous adenoma as a well-defined nodule. Microscopically, sebaceous adenoma presented an increased number of lobules, smaller lobules, and a greater number of germinative/squamous cells. Sebaceous hyperplasia also had an increased number of lobules and fewer number of germinative/squamous cells, as compared to normal oral sebaceous glands. Ki-67 expression was seen only in germinative cells and counts were higher in sebaceous adenomas followed by hyperplasias and normal glands. Conclusions. Sebaceous hyperplasias and adenomas showed different clinical, microscopic, and proliferative characteristics, suggesting the usefulness of the studied criteria on diagnosis of these uncommon oral lesions. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107: 100-104)
Country: EUA
Editor: Mosby-elsevier
Citation: Oral Surgery Oral Medicine Oral Pathology Oral Radiology And Endodontology. Mosby-elsevier, v. 107, n. 1, n. 100, n. 104, 2009.
Rights: fechado
Identifier DOI: 10.1016/j.tripleo.2008.09.027
Date Issue: 2009
Appears in Collections:Unicamp - Artigos e Outros Documentos

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