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Type: Artigo de periódico
Title: Taste disorders and oral evaluation in patients undergoing allogeneic hematopoietic SCT
Author: Boer, CC
Correa, MEP
Miranda, ECM
de Souza, CA
Abstract: The aim of this study was to evaluate taste perception, salivary flow rate and oral pathologies in three different groups of patients undergoing hematopoietic SCT (HSCT) classified according to time post transplant. Group I (n = 20) up to 150 days after HSCT, group II (n = 20) between 151 and 1095 days and group III (n = 21) more than 1095 days. Taste acuity was measured by four basic tastes of four solutions, in three concentrations (M): NaCl, sucrose, citric acid and caffeine. Patients classified flavors as sweet, sour, salty, bitter and without. flavor. The intensity was considered high, medium and low. Unstimulated saliva was collected and salivary flow rates (ml/min) were determined. Of 61 patients, 31 had chronic GVHD. For the sweet solution, the high and low concentrations represented a challenge for those patients. No patients were sensitive to the low concentration of caffeine solution (P = 0.05). Saliva flow rate was diminished in 10 of 61(P(P =0.05). Saliva flow rate was diminished in 10 of 61 =0.05). Saliva flow rate was diminished in 10 of 61 (16%) patients and hyposalivation was more intense in groups II/III (P = 0.007). There was no correlation between taste dysfunction and oral chronic GVHD. The results indicated taste alterations only for the sweet and salty tastes even in patients up to 3 years after HSCT and may not correlate with oral chronic GVHD and with hyposalivation. Bone Marrow Transplantation (2010) 45, 705-711; doi:10.1038/bmt.2009.237; published online 21 September 2009
Subject: taste disorders
oral health
allogeneic HSCT
Country: Inglaterra
Editor: Nature Publishing Group
Citation: Bone Marrow Transplantation. Nature Publishing Group, v. 45, n. 4, n. 705, n. 711, 2010.
Rights: fechado
Identifier DOI: 10.1038/bmt.2009.237
Date Issue: 2010
Appears in Collections:Unicamp - Artigos e Outros Documentos

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