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Type: Artigo de periódico
Title: Colon Cancer and Swimming Exercise: Effect on Wistar Rat Testes
Author: de Freitas, KM
Natali, AJ
Lunz, W
Costa, KLC
Leite, RP
Dolder, H
da Matta, SLP
Abstract: This study was undertaken to determine whether colon cancer (CC) and chronic swimming exercise alter rat testis. Eleven weeks old rats were distributed into control group (n=6) and the groups that were induced to develop CC by dimethylhydrazine injections (nEG, EG0, EG2 and EG4; n=10 each group). In the group nEG, the rats did not swim, whereas groups EGO, EG2 and EG4, underwent a swimming program with distinct loads (0, 2 and 4% of body mass, respectively) for 35 weeks. The morphometry, stereology and cell counts showed damage caused by the CC on the germ epithelium. These results were noteworthy since this was the first report to associate the CC with testicular damage. Swimming exercise had no significant role in reducing, or increasing the CC effects on the testis, despite having slightly improved the testis structure of the exercised rats without load. In conclusion, CC caused testis impairment, which could not be avoided by the swimming exercise.
Subject: 1,2-dimethylhydrazine
Country: Brasil
Editor: Inst Tecnologia Parana
Citation: Brazilian Archives Of Biology And Technology. Inst Tecnologia Parana, v. 56, n. 4, n. 557, n. 566, 2013.
Rights: aberto
Identifier DOI: 10.1590/S1516-89132013000400005
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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