Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/78936
Type: Artigo de periódico
Title: Collagen birefringence in skin repair in response to red polarized-laser therapy
Author: Silva, DFT
Vidal, BC
Zezell, DM
Zorn, TM
Nunez, SC
Ribeiro, MS
Abstract: We use the optical path difference (OPD) technique to quantify the organization of collagen fibers during skin repair of full-thickness burns following low-intensity polarized laser therapy with two different polarization incidence vectors. Three burns are cryogenerated on the back of rats. Lesion L-parallel to is irradiated using the electric field vector of the polarized laser radiation aligned in parallel with the rat's occipital-caudal direction. Lesion L-perpendicular to is irradiated using the electric field vector of the polarized laser radiation aligned perpendicularly to the aforementioned orientation. Lesion C is untreated. A healthy area labeled H is also evaluated. The tissue samples are collected and processed for polarized light microscopy. The overall finding is that the OPD for collagen fibers depends on the electric field vector of the incident polarized laser radiation. No significant differences in OPDs are observed between L-parallel to and H in the center, sides, and edges of the lesion. Lesions irradiated using the electric field vector of the polarized laser radiation aligned in parallel with the rat's occipital-caudal direction show higher birefringence, indicating that collagen bundles in these lesions are more organized. (c) 2006 Society of Photo-Optical Instrumentation Engineers.
Subject: birefringence
burn
collagen
laser
polarization
skin
Country: EUA
Editor: Spie-soc Photo-optical Instrumentation Engineers
Rights: aberto
Identifier DOI: 10.1117/1.2187418
Date Issue: 2006
Appears in Collections:Unicamp - Artigos e Outros Documentos

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