Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/78908
Type: Artigo de periódico
Title: Synthesis, spectroscopic characterizations and antimicrobial activity of copper and zinc complexes of levofloxacin, ciprofloxacin and 3-carboxy-4-quinolone
Author: Huber, PC
Reis, GP
Amstalden, MCK
Lancellotti, M
Almeida, WP
Abstract: Copper and zinc complexes based on levofloxacin, ciprofloxacin and 3-carboxy-4-quinolone with molecular formula IM(C18H19FN3O4)(2)].2H(2)O, [M(C-17 H17FN3O3)(2)].2H(2)O and [M(C10H6NO3)].2H2O, respectively, were synthesized by the reaction of copper or zinc nitrate and the corresponding ligand. Complexes were not obtained as single crystals. Infrared spectroscopy, high resolution mass spectrometry and thermogravimetric analysis are also performed. Except in the case of copper complexes, H-1 and C-13 NMR spectra were obtained. Antimicrobial activity of complexes and their ligands are carried out against a panel of microorganism from ATCC cultures and strains from clinical isolate were also included. All complexes showed moderate to good antimicrobial activity depending on the concentration. (C) 2013 Elsevier Ltd. All rights reserved.
Subject: Copper complexes
Zinc complexes
Quinolones
Antimicrobial activity
Country: Inglaterra
Editor: Pergamon-elsevier Science Ltd
Rights: fechado
Identifier DOI: 10.1016/j.poly.2013.04.007
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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