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Type: Artigo de periódico
Title: Temporal relationship between sucrose-associated changes in dental biofilm composition and enamel demineralization
Author: Vale, GC
Tabchoury, CPM
Arthur, RA
Del Bel Cury, AA
Leme, AFP
Cury, JA
Abstract: The aim of this study was to investigate the temporal relationship between changes in biofilm composition and enamel demineralization following exposure to sucrose. A crossover blind study was conducted in situ in three phases, during which 12 volunteers, divided into three groups, subjected enamel slabs 8 times/day to water ( negative control), 10% glucose + 10% fructose ( active control) or 20% sucrose solution. Biofilms accumulated for 3, 7 and 14 days were collected and analyzed biochemically and microbiologically, and mineral loss from enamel (Delta Z) was evaluated. Significantly higher (Delta Z) was found in the sucrose group after 7 days. However, on the 3rd day, lactobacilli, insoluble extracellular polysaccharide (EPS) and intracellular polysaccharide were significantly higher, and the calcium, inorganic phosphorus and fluoride concentrations in the biofilm were significantly lower in the sucrose group than in the negative controls. The only significant difference compared to glucose + fructose treatment was a higher insoluble EPS concentration. The data suggest that, although sucrose induces significant enamel demineralization only after 7 days of biofilm accumulation, changes in the biofilm composition are observed earlier. Copyright (c) 2007 S. Karger AG, Basel
Subject: biofilm
enamel demineralization
Country: Suíça
Editor: Karger
Citation: Caries Research. Karger, v. 41, n. 5, n. 406, n. 412, 2007.
Rights: fechado
Identifier DOI: 10.1159/000105764
Date Issue: 2007
Appears in Collections:Unicamp - Artigos e Outros Documentos

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