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|Type:||Artigo de periódico|
|Title:||Texture analysis of magnetic resonance images of patients with juvenile myoclonic epilepsy|
|Author:||de Oliveira, MS|
|Abstract:||Background/purpose: Juvenile myoclonic epilepsy (JME) is the most frequent subsyndrome of the idiopathic generalized epilepsies, and experimental investigations support that the thalamus is a key structure in the mechanisms of JME. Texture analysis (TA) is an image processing technique which can be used to characterize images such as MRI. Objective: The goal of this work was to investigate the thalamus of patients with JME using TA, a quantitative neuroimaging technique. Methods: Patients and controls were submitted to MRI investigation. Images were acquired in a 2-Tesla scanner. The T1 volumetric sequence was used for thalamic segmentation and extraction of texture parameters. Twenty-four patients with a diagnosis of JME and 20 healthy volunteers were investigated. Results: Texture analysis revealed differences between the right thalamus of patients and controls. Conclusions: The present investigation supports the participation of the thalamus in the disease mechanisms of JME. Texture analysis may be a useful tool in the quantitative neuroimaging investigation of the epilepsies and can be important to understand JME. (C) 2012 Elsevier Inc. All rights reserved.|
|Subject:||Juvenile myoclonic epilepsy (JME)|
|Editor:||Academic Press Inc Elsevier Science|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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