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|Type:||Artigo de periódico|
|Title:||Lead Deposition in Bovine Enamel during a pH-Cycling Regimen Simulating the Caries Process|
|Author:||MOLINA, G. F.|
ALMEIDA, G. R. Costa de
GUERRA, C. de Souza
CURY, J. A.
ALMEIDA, A. P. de
BARROSO, R. C.
GERLACH, R. F.
|Abstract:||Like fluoride, lead (Pb) accumulates on the enamel surface pre-eruptively, but it is not yet known whether it also deposits on enamel while dental caries is developing. This study evaluates Pb distribution in bovine enamel slabs submitted to a pH-cycling regimen simulating the caries process. The slabs were subjected to 8 cycles of de- and remineralizing conditions, and Pb (as acetate salt) was added to the de- and remineralized solutions at concentrations of 30 mu g/l (experimental group, E1) and 300 mu g/l (experimental group, E2). The control group (C) consisted of solutions to which Pb was not added. After the pH cycling, 100-mu m sections of the slabs were analyzed by polarizing microscopy, to observe the extent of caries-like lesions, and these sections were used for Pb estimation by Synchrotron radiation X-ray microfluorescence. Caries lesions were observed along all superficial enamel surfaces to an extent of 120 mu m. A Pb concentration gradient was observed in enamel, which decreased toward dentine. The highest Pb signals were observed for group E2, and the differences were statistically significant at enamel depths of 0 (C vs. E2; p = 0.029) and 50 mu m (C vs. E2 and E1 vs. E2; p = 0.029). In conclusion, this study suggests that if Pb is present in the oral environment, it may deposit in enamel during the caries process. Copyright (C) 2011 S. Karger AG, Basel|
Synchrotron radiation X-ray microfluorescence
Teeth and caries
|Citation:||CARIES RESEARCH, v.45, n.5, p.469-474, 2011|
|Appears in Collections:||FOP - Artigos e Outros Documentos|
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