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Type: Artigo de periódico
Title: Antioxidant and antimicrobial activities of aporphinoids and other alkaloids from the bark of Annona salzmannii A. DC. (Annonaceae)
Author: Costa, EV
da Cruz, PEO
de Lourenco, CC
Moraes, VRD
Nogueira, PCD
Salvador, MJ
Abstract: The antioxidant capacity by oxygen radical absorbance capacity (ORAC)-FL method and antimicrobial activity using the broth microdilution method of aporphinoids (liriodenine 1, anonaine 2 and asimilobine 3) and other alkaloids (reticuline 4 and cleistopholine 5) isolated from the bark of Annona salzmannii A. DC. (Annonaceae) were evaluated. For antioxidant activity, the most active alkaloid was asimilobine with ORAC value of 2.09 relative trolox equivalents. For antimicrobial activity, some alkaloids showed significant minimal inhibitory concentration (MIC) values in the range of 25-100 mu gmL(-1). The most active compounds were the aporphinoids liriodenine, anonaine and asimilobine, some of them more active than the positive control.
Subject: Annona salzmannii
benzyltetrahydroisoquinoline alkaloid
azaanthracene alkaloid
antioxidant and antimicrobial activities
Country: Inglaterra
Editor: Taylor & Francis Ltd
Citation: Natural Product Research. Taylor & Francis Ltd, v. 27, n. 11, n. 1002, n. 1006, 2013.
Rights: fechado
Identifier DOI: 10.1080/14786419.2012.688044
Date Issue: 2013
Appears in Collections:Unicamp - Artigos e Outros Documentos

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