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Type: Artigo de periódico
Title: Total synthesis of the potent immunosuppressant (-)-Pironetin
Author: Dias, LC
de Oliveira, LG
de Sousa, MA
Ellensohn, RM
Abstract: A convergent and efficient total synthesis of (-)-pironetin, a compound that shows plant growth regulatory activity, and is immunosuppressive as well as having remarkable antitumoral activity, is described. The synthesis required 19 steps from N-propionyl oxazolidinone (S)-9 and produced the desired product in 11% overall yield.
Subject: immunosuppressive activity
antitumoral activity
unsaturated lactone
total synthesis
Country: EUA
Editor: Arkat Usa Inc
Rights: aberto
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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