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|Type:||Artigo de periódico|
|Title:||Topology of a ternary complex (proparacaine-beta-cyclodextrin-liposome) by STD NMR|
de Paula, E
|Abstract:||The topologies of proparacaine (PPC) in fl-cycloclextrin (fl-CID), PPC in egg phosphaticly1choline (EPQ liposomes and PPC in fl-CD in EPC were investigated using NMR experiments (I D ROESY and saturation transfer difference (STD)). This is the first description of the STID technique applied to PPC - EPC -P-CD system, revealing that not only PPC was imbedded in EPC bilayer, but fl-CD was also interacting with liposome vesicles. These results are novel and were rationalized as the spontaneous formation of a ternary complex with some fl-CD molecules bound to external liposome vesicles surfaces. Copyright (c) 2008 John Wiley & Sons, Ltd.|
|Editor:||John Wiley & Sons Ltd|
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
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