Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/77729
Type: Artigo de periódico
Title: Topology of a ternary complex (proparacaine-beta-cyclodextrin-liposome) by STD NMR
Author: Cabeca, LF
Fernandes, SA
de Paula, E
Marsaioli, AJ
Abstract: The topologies of proparacaine (PPC) in fl-cycloclextrin (fl-CID), PPC in egg phosphaticly1choline (EPQ liposomes and PPC in fl-CD in EPC were investigated using NMR experiments (I D ROESY and saturation transfer difference (STD)). This is the first description of the STID technique applied to PPC - EPC -P-CD system, revealing that not only PPC was imbedded in EPC bilayer, but fl-CD was also interacting with liposome vesicles. These results are novel and were rationalized as the spontaneous formation of a ternary complex with some fl-CD molecules bound to external liposome vesicles surfaces. Copyright (c) 2008 John Wiley & Sons, Ltd.
Subject: NMR
H-1 NMR
1D ROESY
DOSY
STD
proparacaine
beta-cyclodextrin
liposome
topology
inclusion complex
Country: Inglaterra
Editor: John Wiley & Sons Ltd
Rights: fechado
Identifier DOI: 10.1002/mrc.2265
Date Issue: 2008
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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