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|Type:||Artigo de periódico|
|Title:||ANTI-IL-10 TREATMENT DOES NOT BLOCK EITHER THE INDUCTION OR THE MAINTENANCE OF ORALLY INDUCED TOLERANCE TO OVA|
|Abstract:||Herein, the role of IL-10 in the induction and maintenance of oral tolerance was evaluated. The results show that: (1) mice treated with MoAb anti-IL-10 are permissive to the induction of oral tolerance to OVA; (2) anti-IL-10 treatment did not reverse the in vitro blocking of T cell proliferative response found in orally-tolerized mice; and (3) orally-induced tolerance could not be broken by anti-IL-10 treatment. Taken together, these results suggest that IL-10 is not a fundamental cytokine for the establishment and maintenance of oral tolerance.|
|Editor:||Blackwell Science Ltd|
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
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