Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/77692
Type: Artigo de periódico
Title: ANTI-IL-10 TREATMENT DOES NOT BLOCK EITHER THE INDUCTION OR THE MAINTENANCE OF ORALLY INDUCED TOLERANCE TO OVA
Author: AROEIRA, LS
CARDILLO, F
DEALBUQUERQUE, DA
VAZ, NM
MENGEL, J
Abstract: Herein, the role of IL-10 in the induction and maintenance of oral tolerance was evaluated. The results show that: (1) mice treated with MoAb anti-IL-10 are permissive to the induction of oral tolerance to OVA; (2) anti-IL-10 treatment did not reverse the in vitro blocking of T cell proliferative response found in orally-tolerized mice; and (3) orally-induced tolerance could not be broken by anti-IL-10 treatment. Taken together, these results suggest that IL-10 is not a fundamental cytokine for the establishment and maintenance of oral tolerance.
Country: Inglaterra
Editor: Blackwell Science Ltd
Rights: fechado
Identifier DOI: 10.1111/j.1365-3083.1995.tb03573.x
Date Issue: 1995
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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