Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/76977
Type: Artigo de periódico
Title: AGE-RELATED CHANGES IN DYSTROPHIN-GLYCOPROTEIN COMPLEX AND IN UTROPHIN ARE NOT CORRELATED WITH INTRINSIC LARYNGEAL MUSCLES PROTECTION IN mdx MICE
Author: Ferretti, R
Pertille, A
Neto, HS
Marques, MJ
Abstract: In this study we investigate whether dystrophic intrinsic laryngeal muscles (ILM) from aged mdx mice show alterations in dystrophin-glycoprotein complex (DGC) components. Immunofluorescence and immunoblotting analyses of beta-sarcoglycan, beta-dystroglycan, and utrophin showed that aged ILM had a similar pattern of changes in aged affected muscles (diaphragm and limb), suggesting that aging leads to changes in utrophin and DGC proteins in dystrophic ILM that cannot be correlated with their protection from dystrophic change. Muscle Nerve 44: 978-980, 2011
Subject: beta-dystroglycan
beta-sarcoglycan
Duchenne muscular dystrophy
dystrophin
intrinsic laryngeal muscles
mdx
utrophin
Country: EUA
Editor: Wiley-blackwell
Rights: fechado
Identifier DOI: 10.1002/mus.22235
Date Issue: 2011
Appears in Collections:Unicamp - Artigos e Outros Documentos

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