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|Type:||Artigo de periódico|
|Title:||Adsorption of plasma proteins to DMAA hydrogels obtained by ionizing radiation and its relationship with blood compatibility|
|Abstract:||The interaction of plasma proteins such as albumin, gamma-globulin, and fibrinogen with the surface of graft copolymers DMAA-G-PTFE, DMAA-G-PETFE, and DMPLA-G-PE obtained by radiation graft polymerization was studied. The adsorption of serum proteins was affected by the hydrophilicity of the graft copolymers. Increased albumin adsorption and decreased fibrinogen and gamma-globulin adsorption with increasing grafting levels was shown. A certain range of degrees of grafting showed an improved blood compatibility of the polymeric surfaces due to the existence of a hydrophilic/hydrophobic balance on the polymers. The results suggest that the DMAA-G-PTFE, DMAA-G-PETFE, and DMAA-G-FE graft copolymers can be used as biomaterials for longterm use in cardiovascular systems.|
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
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