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Type: Artigo de periódico
Title: Characterization of language and reading skills in familial polymicrogyria
Author: OLIVEIRA, Ecila Paula Mesquita
HAGE, Simone Rocha Vasconcelos
GUIMARAES, Catarina Abraao
GUERREIRO, Carlos Alberto
TEIXEIRA, Karine Couto Sarmento
MONTENEGRO, Maria Augusta
CENDES, Fernando
GUERREIRO, Marilisa Mantovani
Abstract: Polymicrogyria (PMG) is a malformation of cortical development characterized by an excessive number of small gyri and abnormal cortical lamination, giving the cortical surface an irregular and gross appearance. The severity of clinical manifestations correlates with the extent of cortical involvement. The objective of the present study was to describe three families with linguistic features of developmental language disorder and reading impairment, and to establish a neuroanatomic correlation through neuroimaging. Subjects have been submitted to a comprehensive protocol including psychological assessment, language evaluation, neurological examination, and neuroimaging investigation. In our families, children usually had the diagnosis of developmental language disorder while adults had the diagnosis of reading impairment. MRI showed perisylvian polymicrogyria in several subjects of each family. Our data support the idea that there is a co-occurrence of developmental language disorder and reading impairment and both conditions may be associated with polymicrogyria. (c) 2007 Elsevier B.V. All rights reserved.
Subject: developmental language disorder
reading impairment
malformation of cortical development
Country: Holanda
Citation: BRAIN & DEVELOPMENT, v.30, n.4, p.254-260, 2008
Rights: fechado
Identifier DOI: 10.1016/j.braindev.2007.08.010
Date Issue: 2008
Appears in Collections:FCM - Artigos e Outros Documentos

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