Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/76763
Type: Artigo de periódico
Title: Two intermediates in the synthesis of decahydroisoquinolines with NMDA and AMPA receptor antagonist activity
Author: Zukerman-Schpector, J
Vega, M
Caracelli, I
Dias, LC
Fernandes, AMAP
Abstract: In 6-methyl-N-(4-nitrobenzoyl)-5,6-dihydropyridin-2(1H)one, C13H12N2O4, (I), the piperidone ring is in a distorted half-chair conformation. In 8-methoxy-3-methyl-N-(4-nitrobenzoyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline-1,6-dione, C18H20N2O6, (II), the heterocyclic ring is in a slightly distorted half-boat conformation, while the other six-membered ring is in a distorted chair conformation. Compound (II) presents a strong intramolecular C-H . . .O hydrogen bond. In both (I) and (II), the molecules interact through C-H . . .O interactions.
Country: Dinamarca
Editor: Munksgaard Int Publ Ltd
Rights: aberto
Identifier DOI: 10.1107/S0108270101009702
Date Issue: 2001
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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