Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/767
Type: Artigo de periódico
Title: Congenital Bilateral Perisylvian Syndrome: Familial Occurrence, Clinical and Psycholinguistic Aspects Correlated with MRI
Author: BRANDAO-ALMEIDA, I. L.
HAGE, S. R. V.
OLIVEIRA, E. R. M.
GUIMARAES, C. A.
TEIXEIRA, K. C. S.
ABRAMIDES, D. V. M.
MONTENEGRO, M. A.
SANTOS, N. F.
CENDES, F.
LOPES-CENDES, I.
GUERREIRO, M. M.
Abstract: Objective: Congenital bilateral perisylvian syndrome (CBPS) is frequently caused by polymicrogyria (PMG). The aim of this study was to correlate the clinical and psycholinguistic aspects with neuroradiological data of patients with CBPS. Methods: Thirty-one patients were studied. We performed a clinical investigation of the patients and their families, including MRI scanning, neuropsychological tests and language evaluation. Results: The statistical analysis showed that: a) prenatal events are associated with the non-familial type of PMG; b) diffuse PMG is associated with pseudobulbar signs, as opposed to BPPP; c) motor deficit is associated with diffuse PMG; d) epilepsy is equally present in patients with both familial or non-familial PMG, but is more frequently seen in patients with diffuse PMG; e) dyslexia and SLI can be a feature of both the diffuse or BPPP, and either familial or sporadic cases of PMG. Conclusions: The severity of clinical manifestations in CBPS is correlated with the extent of cortical involvement. Most patients with CBPS have a history of speech delay or language difficulties and no epilepsy. Dyslexia can be found in patients with PMG.
Subject: epilepsy
polymicrogyria
malformations of cortical development
congenital bilateral perisylvian syndrome
dyslexia
specific language impairment
Country: Alemanha
Editor: GEORG THIEME VERLAG KG
Citation: NEUROPEDIATRICS, v.39, n.3, p.139-145, 2008
Rights: fechado
Identifier DOI: 10.1055/s-0028-1085462
Address: http://apps.isiknowledge.com/InboundService.do?Func=Frame&product=WOS&action=retrieve&SrcApp=EndNote&UT=000261117700001&Init=Yes&SrcAuth=ResearchSoft&mode=FullRecord
http://dx.doi.org/10.1055/s-0028-1085462
Date Issue: 2008
Appears in Collections:FCM - Artigos e Materiais de Revistas Científicas

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