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Type: Artigo de periódico
Title: Daily variations in human plasma fluoride concentrations
Author: CARDOSO, Vanessa E. S.
AOYAMA, Hiroshi
BUZALAF, Marilia A. R.
Abstract: This study investigated the variations in human plasma fluoride concentrations ([F]) and sought to determine the causes. Five subjects (27-33 years old) received a low-F diet during the 5 days of the study. Plasma samples and urine were collected every 3 h from 8 a.m. to 8 p.m. F, PTH, Ca and P were analyzed with the electrode, by chemiluminescence, AAS and colorimetry, respectively. A trend for the plasma [F] was found. The peak [F], 0.55 +/- 0.11 mu mol L(-1), occurred at 11 a.m. and the lowest [F], 0.50 +/- 0.06 mu mol L(-1) occurred between 5 and 8 p.m. Plasma [F] were positively correlated with urinary F excretion rates and with serum PTH levels, but not with the Ca or P levels. Serum PTH levels were positively correlated with urinary F excretion rates and negatively correlated with plasma Ca. The results suggest that the renal system seems to control the daily fluctuations in plasma [F]. (c) 2008 Elsevier B.V. All rights reserved.
Subject: Fluoride
Biological rhythm
Renal system
Country: Suiça
Citation: JOURNAL OF FLUORINE CHEMISTRY, v.129, n.12, p.1193-1198, 2008
Rights: fechado
Identifier DOI: 10.1016/j.jfluchem.2008.09.008
Date Issue: 2008
Appears in Collections:IB - Artigos e Outros Documentos

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