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Type: Artigo de periódico
Title: Studies of the Deracemization of (+/-)-2-hydroxy-1-tetralone by Trichosporon cutaneum
Author: Lunardi, I
Cazetta, T
Conceicao, GJA
Moran, PJS
Rodrigues, JAR
Abstract: The diastereo- and enantioselective bioreduction of (+/-)-2-hydroxy-1-tetralone (6) to the corresponding enantiopure (1S,2R)-cis-1,2-dihydroxy-1,2,3,4-tetrahydronaphthalene (1) (83 % isolated yield, > 99 % ee), mediated by resting cells of the yeast Trichosporon cutaneum CCT 1903 through dynamic kinetic resolution is reported. Deracemization of (+/-)-6 was observed in kinetic studies on the biotransformation of the enantiomers (R)-6 and (S)-6.
Subject: amino alcohols
Trichosporon cutaneum
Country: Alemanha
Editor: Wiley-v C H Verlag Gmbh
Rights: fechado
Identifier DOI: 10.1002/adsc.200600331
Date Issue: 2007
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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