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Type: Artigo de periódico
Title: The effect of different doses of propofol on tracheal intubating conditions without muscle relaxant in children
Author: Braga, ADD
Braga, FSD
Poterio, GMB
Filier, PR
Cremonesi, E
Abstract: Background and objective Situations may occur in anaesthetic practice where the use of neuromuscular blocking drugs is unsuitable or contraindicated. We investigated the use of propofol given 5 min after fentanyl to perm it endotracheal intubation in children. Methods We studied the intubating conditions and cardiovascular parameters in 60 ASA I and II children. intravenous midazolam (0.1 mg kg(-1)) was given as premedication 5 min before the induction of anaesthesia. The children received different doses of propofol (group I, 2.5 mg kg(-1); group II, 3.0 mg kg(-1); group III, 3.5 mg kg(-1)) preceded by fentanyl (3.0 mug kg(-1)) given 5 min earlier. No neuromuscular blocking agents were administered. The intubating conditio ns were assessed using a four-point scoring system based on the degree of difficulty of laryngoscopy, the position of vocal cords and the intensity of coughing. Results Tracheal intubating conditions were adequate in 20% of the patients in group I, in 75% of the patients in group II and in 80% of the patients in group III (P<0.05 for group I vs. groups II and III). Haemodynamic changes were not significantly different between the groups. Conclusions Propofol (3.0 mg kg(-1)) preceded by fentanyl (3.0 <mu>g kg(-1)) was adequate for the induction of anaesthesia in children and provided adequate tracheal intubating conditions without significant haemodynamic changes. This method represents a useful alternative technique for tracheal intubation when neuromuscular blocking drugs are contraindicated or should be avoided.
Subject: anaesthesia, general
intubation, intratracheal
anaesthetics, intravenous, propofol
adjuvants, anaesthesia, fentanyl
anaesthetics, intravenous, fentanyl
Country: Inglaterra
Editor: Blackwell Science Ltd
Rights: fechado
Date Issue: 2001
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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