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|Type:||Artigo de periódico|
|Title:||Simple fluorescent PCR method for detection of large deletions in the beta-globin gene cluster|
|Author:||De Andrade, TG|
|Abstract:||We developed a semi-automated approach to detect large deletions in the beta-globin gene cluster, based on the quantitative differences in the amplifications of samples by a fluorescent PCR. With this strategy, we were able to detect the presence of HPFH-2 in an African-Brazilian subject, confirmed by sequencing analysis. Differently from other PCR strategies, GAP-PCR for example, it has the potential to identify new deletions. (C) 2003 Wiley-Liss, Inc.|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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