Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/73798
Type: Artigo de periódico
Title: The effects of Chlorella vulgaris in the protection of mice infected with Listeria monocytogenes. Role of natural killer cells.
Author: Dantas, DCM
Kaneno, R
Queiroz, MLS
Abstract: In this work we have demonstrated the effects of oral administration of Chlorella vulgaris (CV) on Natural Killer cells (NK) activity of mice infected with a sublethal dose of viable Listeria monocytogenes. The treatment with C. vulgaris produced a significant increase on NK cells activity in normal (non-infected) animals compared to the animals that received only vehicle (water) (p < 0.0001). Similarly, the infection alone produced a significant increase on NK cells activity, which was observed at 48 and 72 hours after the inoculation of L. monocytogenes. Moreover, when CV was administered in infected animals, there was an additional increase inn NK cells activity which was significantly higher than that found in the infected groups (p < 0.0001). CV treatment (50 and 500mg/Kg) of mice infected with a dose of 3x10(5) bacteria/animal, which was lethal for all the non- treated controls, produced a dose-response protection which led to a 20% and 55% survival, respectively (p < 0.0001).
Country: EUA
Editor: Marcel Dekker Inc
Rights: fechado
Identifier DOI: 10.3109/08923979909007129
Date Issue: 1999
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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