Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/72625
Type: Artigo de periódico
Title: The use of violacein to study biochemical behaviour of Saccharomyces cerevisiae cells
Author: Pereira, RDS
Duran, N
Volpe, PLO
Abstract: Violacein, a biochemical compound produced by Chromobactarium violaceum which has antichagasic properties, was used to study biochemical behaviour of Saccharomyces cerevisiae cells. At 20 mu M and 40 mu M, violacein did not alter the membrane potential (Delta Psi) of S. cerevisae cells, which means that the integrity of the cell membrane was maintained. On the other hand, at 60 mu M and 80 mu M, violacein produced significant alterations in the membrane potential. This information will be very useful in using S. cerevisiae cells as a model to test the toxicity of new drugs before using in animals or human beings.
Subject: Saccharomyces cerevisiae
violacein
NAD(P)H
Chromobaterium violaceum
citochrome C
oxygen
consumption
Chagas' Disease
Country: Suíça
Editor: Medecine Et Hygiene
Rights: fechado
Date Issue: 2005
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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