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|Type:||Artigo de periódico|
|Title:||The relationship between ABO groups and subgroups, factor VIII and von Willebrand factor|
|Abstract:||The aim of this study was to correlate ABO groups with plasma levels of factor Vill (FV111), von Willebrand factor (VWF:Ag), and ristocetin cofactor (VWF:RCo). Serological and molecular tests defined blood groups from 114 donors (10 AA, 10 BB, 10 AB, 10 A0(1), 10 B0(1), 16 0(1)0(1), 20A(2)0(1), 20 A(2)B, 4 A(3)0(1), 3A(x)0(1), and 1 B(el)0(1)). The levels of VWF:Ag, FV111 and VWF:RCo observed in rare subgroups (A(3)0(1), A(x)0(1), B(el)0(1)) were similar to the values found in the 0101 group. However, levels of these factors were significantly higher in A(2)0(1) donors than in 0(1)0(1) donors (VWF:Ag p=0.01; FV111 p=0.04; VWF:RCo p < 0.001). Strong correlations were demonstrated between plasma levels of VWF:Ag and FV111 (R=0.77; p=0.001) and between VWF:Ag and VWF:RCo (R=0.75; P=0.001).|
von Willbrand factor
|Editor:||Ferrata Storti Foundation|
|Appears in Collections:||Unicamp - Artigos e Outros Documentos|
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