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|Type:||Artigo de periódico|
|Title:||The potential of extracts of Caryocar villosum pulp to scavenge reactive oxygen and nitrogen species|
|Abstract:||Caryocar villosum (piquid) is a native fruit from the Amazonian region, considered to be an interesting source of bioactive compounds. In this paper, five extracts of C. villosum pulp were obtained, using solvents with different polarities and their in vitro scavenging capacity against reactive oxygen species (ROS) and reactive nitrogen species (RNS) was determined. Additionally, the phenolic compounds and carotenoids in each extract were identified and quantified by a high performance liquid chromatography coupled to diode array and mass spectrometer detectors (HPLC-DAD-MS/MS). The ethanol/water and water extracts, which presented the highest phenolic contents (5163 and 1745 mu g/g extract, respectively), with ellagic acid as the major phenolic compound, proved to have the highest ROS and RNS scavenging potential. Nevertheless, in general, ellagic acid was less effective in scavenging ROS (IC50 from 1.7 to 108 mu g/ml) and RNS (IC50 from 0.05 to 0.59 mu g/ml), when compared to gallic acid (IC50 from 0.4 to 226 mu g/ml for ROS and IC50 from 0.04 to 0.12 mu g/ml for RNS). The results obtained in the present study clearly demonstrated that the in vitro antioxidant efficiency of C. villosum extracts was closely related to their contents of phenolic compounds. (C) 2012 Elsevier Ltd. All rights reserved.|
|Editor:||Elsevier Sci Ltd|
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
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