Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/72110
Type: Artigo de periódico
Title: Spectroscopic and theoretical studies of some N,N-diethyl-2-[(4-substituted)phenylsulfinyl] acetamides
Author: Olivato, PR
Vinhato, E
Rodrigues, A
Zukerman-Schpector, J
Rittner, R
Dal Colle, M
Abstract: The analysis of the IR carbonyl bands of the N,N-diethyl-2-[(4-substituted)phenylsulfinyl] acetamides Et2NC(O)CH2S(O)Ph-Y (Y = OMe 1, Me 2, H 3, Cl 4, Br 5 and NO2 6) and the parent N,N-diethylacetamide 7, supported by HF/6-31 G** ab initio calculations of 3 and 7, indicated the existence of two pairs of cis (anti, syn) and gauche (anti, syn) conformers in gas phase, being the cis conformer pair more stable than the gauche pair. As in the case of the parent amide 7, the anti geometry is more stable than the syn one, for each pair of cis and gauche conformers. The higher stability of the cis conformer pair is in line with its geometry which allows a strong O-(CO)(delta-)...S-(SO)(delta+) charge transfer and Coulombic interactions along with the O-(CO)(delta-) ...ortho-H-(Ph)(delta+) electrostatic interaction (intramolecular hydrogen bond). The gauche conformer pair is weakly stabilized through the 0'- -. (SO) (CO) Coulombic interaction. The single carbonyl band found in solution (solvents of increasing relative permittivity) may be ascribed to the more stable and more polar cis conformer pair. The negative carbonyl frequency shifts of ca. -11 cm(-1) (in n-hexane) for compounds 1-5 give further support for the simultaneous occurrence of the O-(CO)(delta-) ...S-(CO)(delta+) and O-(CO)(delta-)... ortho-H-(Ph)(delta+) interactions, which stabilize the cis conformer pair. X-ray single crystal analysis performed on 6 indicates that this compound assumes in the crystal a quasi-gauche (q-g) conformation and the N,N-diethyl groups the anti geometry. The (q-g) conformation is stabilized in the solid by crossed O-(CO)delta-... S-(SO)(delta+) and O-(SO)(delta-) ... C-(CO)(delta+) orbital and Coulombic inter actions. In order to obtain the large energy gain from the crystal packing, the q-g conformer forms centro-symmetric dimers which results in infinite chains stabilized by intermolecular hydrogen bonds. (c) 2006 Elsevier B.V. All rights reserved.
Subject: infrared spectroscopy
conformational analysis
Ab initio calculations
X-ray diffraction analysis
N,N-diethyl-2-[(4-substituted) phenylsulfinyl acetamides
Country: Holanda
Editor: Elsevier Science Bv
Rights: fechado
Identifier DOI: 10.1016/j.molstruc.2006.05.006
Date Issue: 2007
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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