Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/71559
Type: Artigo de periódico
Title: Screening of Metarhizium spp. strains for anticancer indolizidine alkaloid production and its rapid detection by MS analysis
Author: Justo, OR
Calheiros, CS
Perez, VH
Alegre, RM
Abstract: Six fungi strains ( M. anisopliae 3935, 4516, 4819, PL57, PL43 and M. flavoviride CG291) were studied regarding their ability to produce an anticancer indolizidine alkaloid. The culture process was carried out in Shaken flask at 26 C and 200 rpm using three different culture medium containing oat meal extract supplemented with glucose and DL-lysine or Czapek culture medium. The mycelial extracts produced by Metarhizium spp. cultures were directly submitted to electrospray ionization mass spectrometry ( ESI-MS) analysis and the highest alkaloid concentration ( approximately, 6 mg.L-1) was reached when M. anisopliae 3935 was tested.
Subject: M. anisopliae
M. flavoviride
anticancer
alkaloid
fermentation
Country: Brasil
Editor: Soc Brasileira Microbiologia
Rights: aberto
Identifier DOI: 10.1590/S1517-83822007000400035
Date Issue: 2007
Appears in Collections:Unicamp - Artigos e Outros Documentos

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