Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/71345
Type: Artigo de periódico
Title: Selective and Efficient Mitochondrial Staining with Designed 2,1,3-Benzothiadiazole Derivatives as Live Cell Fluorescence Imaging Probes
Author: Neto, BAD
Correa, JR
Carvalho, PHPR
Santos, DCBD
Guido, BC
Gatto, CC
de Oliveira, HCB
Fasciotti, M
Eberlin, MN
da Silva, EN
Abstract: Novel designed 2,1,3-benzothiadiazole fluorescent probes were synthesized, characterized and applied as live cell fluorescence imaging probe staining only mitochondria in mammalian cancer cell lines (MCF-7). The efficiency of these new probes was found to be much superior to that of the commercially available MitoTracker (R) Red. Cellular and in vitro experiments allowed better understanding of the relationship between the planned molecular architecture of the new dyes and the observed cellular selectivity.
Subject: benzothiadiazole
synthesis
mitochondria
cellular staining
Country: Brasil
Editor: Soc Brasileira Quimica
Rights: aberto
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

Files in This Item:
File Description SizeFormat 
WOS000303444600024.pdf2.52 MBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.