Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/70913
Type: Artigo de periódico
Title: Renal tumor with inferior vena cava thrombus. Surgical approach and prognosis
Author: Denardi, F
Reis, LO
Oliveira, RRM
Ferreira, F
Ferreira, U
Abstract: Objectives: The aim of this study was to evaluate strategies used for surgical management of renal cell carcinoma with tumoral thrombus extension in the inferior vena cava (IVC) and evaluate patient's prognosis. Metods: Fifteen patients with renal tumor and IVC thrombus, under-went radical nephrectomy and thrombectomy, and were retrospectively evaluated. Patients were followed for 0 to 36 months (mean of 9.5 months). Computed tomography (CT) scan with three-dimensional reconstruction was used to define IVC thrombus level. Results: The mean age was 54 years, range from 16 to 79. The thrombus was classified as level I - 13.5%, level II - 40%, level III - 26.5% and level IV - 20%. Surgery was performed with cardiopulmonary bypass (CPB) in six (40%) cases, three (50%) without sternotomy. There was one (13%) death during the intraoperative period; this patient presented extensive metastatic tumor, with the thrombus reaching the right atrium. Patients with lymph node or metastatic disease at initial presentation had poorer overall survival in Kaplan-Meier curve. Both, tumor stage (p = 0.380), and thrombus extension (p = 0.174) were not related to survival. Conclusions: Despite its morbidity and mortality, radical nephrectomy with thrombectomy should be performed in case of renal cell carcinoma with tumoral thrombus, because it can offers the possibility of local control. Patients with lymph node and distant metastatic disease have poor prognoses.
Subject: Inferior vena cava thrombus
Renal tumor
Prognosis
surgical approach
Country: Espanha
Editor: Ene Ediciones Sl
Rights: fechado
Date Issue: 2009
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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