Please use this identifier to cite or link to this item:
|Type:||Artigo de periódico|
|Title:||Probing the mechanism of the Ugi four-component reaction with charge-tagged reagents by ESI-MS(/MS)|
da Silva, WA
de Oliveira, HCB
|Abstract:||The mechanism of the Ugi four-component reaction has been investigated by electrospray ionization (tandem) mass spectrometry using charge-tagged reagents (a carboxylic acid or an amine) to favour detection. Key intermediates were transferred directly via ESI(+) from the reaction solution to the gas phase and characterized by MS measurements and MS/MS collision induced dissociation. The Mumm rearrangement (final step) was also investigated by both travelling wave ion mobility mass spectrometry and DFT calculations. The data seem to consolidate the amazingly selective mechanism of this intricate four-component reaction.|
|Editor:||Royal Soc Chemistry|
|Appears in Collections:||Artigos e Materiais de Revistas Científicas - Unicamp|
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.