Please use this identifier to cite or link to this item: http://repositorio.unicamp.br/jspui/handle/REPOSIP/70086
Type: Artigo de periódico
Title: Preparation and Characterization of a Microwave-Immobilized Fluorinated Stationary Phase for RP-LC
Author: Maldaner, L
Jardim, ICSF
Abstract: A fluorinated stationary phase was prepared through the immobilization of poly(methyl-3,3,3-trifluoropropylsiloxane) onto 5 mu m Kromasil silica by microwave irradiation. The best conditions of immobilization time and temperature were determined by central composite design and response surface methodology. Physical-chemical characterizations (IR, (29)Si NMR and elemental analysis) confirmed that the polymer was attached onto the chromatographic support by different mechanisms that resulted in a percent carbon loading of 10%. Some pharmaceuticals were completely separated with the fluorinated stationary phase using a simple mobile phase while the same separation was not possible with a C18 stationary phase.
Subject: Column liquid chromatography
Microwave immobilization
Experimental design
Stationary phases
Poly(methyl-3,3,3-trifluoropropylsiloxane)
Country: Alemanha
Editor: Springer Heidelberg
Rights: fechado
Identifier DOI: 10.1365/s10337-010-1726-3
Date Issue: 2010
Appears in Collections:Artigos e Materiais de Revistas Científicas - Unicamp

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