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Type: Artigo de periódico
Title: In vitro evaluation of caries inhibition promoted by self-etching adhesive systems containing antibacterial agents
Author: Lobo, MM
Goncalves, RB
Pimenta, LAF
Bedran-Russo, AKB
Pereira, PNR
Abstract: This study evaluated the cariostatic effect of antibacterial self-etching adhesive systems, by means of an in vitro bacterial caries model. Seventy-five prepared bovine slabs were randomly divided into groups (n = 15): (1) unbonded composite, no carious challenge (UNB-NC); (2) unbonded composite, carious challenge (UNB-C); (3) Clearfil SE Bond, no antibacterial agent (CSE); (4) Protect Bond, containing MDPB and fluoride (PB); and (5) Reactmer Bond, fluoride-releasing (RB). All preparations were restored with Filtek (TM) Z-250. Groups (2)-(5) were submitted to a medium containing Streptococcus mutans (ATCC - 25175) for 5 days, and Group (1) was kept in a noninoculated medium. Insoluble polysaccharides present in tooth biofilms were quantified, Knoop hardness (KHN) was measured on the enamel adjacent to restorations, and standard 35-mm polarized light photomicrographs were taken as illustrations. Polysaccharide and Knoop hardness results were analyzed with the use of ANOVA, with a split-split-plot statistical design for KHN. Except for Group (1), all groups showed similar caries formation. Biofilm over PB restorations showed the smallest amounts of polysaccharides (14.37 mu g/mg), and CSE showed the highest amounts (20.87 mu g/mg). All self-etching systems tested were unable to inhibit secondary caries in a bacterial model simulating a high caries challenge, even though there was reduced glucan synthesis provided by the adhesive system containing MDPB and fluoride. (c) 2005 Wiley Periodicals. Inc.
Subject: secondary caries
in vitro microbial caries model
Streptococcus mutans
adhesive systems
Country: EUA
Editor: Wiley-liss
Citation: Journal Of Biomedical Materials Research Part B-applied Biomaterials. Wiley-liss, v. 75B, n. 1, n. 122, n. 127, 2005.
Rights: fechado
Identifier DOI: 10.1002/jbm.b.30312
Date Issue: 2005
Appears in Collections:Unicamp - Artigos e Outros Documentos

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