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Type: Artigo de periódico
Title: In Vitro Degradation of Poly (L-co-D, L lactic acid) Containing PCL-T
Author: Duarte, MAT
Duek, EAD
Motta, AC
Abstract: The application of polymer-based bioresorbable temporary devices in the medical field grows continuously, and professionals from several areas act to solve problems related to body functions lost due to diseases, accidents or natural wear. Here we study the influence from poly(caprolactonetriol) (PCL-T) on the degeneration process in the copolymer poly(L-co-DL-lactic acid) (PLDLA) membrane, by producing PLDLA/PCL-T blends with 90/10, 70/30 and 50/50 relative concentrations. The data for in vitro degradation showed that PCL-T decreases the rate of PLDLA. This was obtained with the following techniques: Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Gel Permeation Chromatography (GPC) and Scanning Electron Microscopy (SEM). Therefore, it is possible to vary the membrane degradation rate by changing the blend composition, which is a tool to tailor a biomaterial.
Subject: Bioresorbable polymer
in vitro degradation
Country: Brasil
Editor: Assoc Brasil Polimeros
Citation: Polimeros-ciencia E Tecnologia. Assoc Brasil Polimeros, v. 24, n. 1, n. 1, n. 8, 2014.
Rights: aberto
Identifier DOI: 10.4322/polimeros.2014.056
Date Issue: 2014
Appears in Collections:Unicamp - Artigos e Outros Documentos

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