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Type: Artigo de periódico
Title: Hydrophilic interaction chromatography
Author: Gama, MR
Silva, RGD
Collins, CH
Bottoli, CBG
Abstract: In the early 1990s, hydrophilic interaction (liquid) chromatography (HILIC) emerged as a new separation method. HILIC is becoming increasingly popular for the separation of polar compounds in aqueous-organic mobile phases rich in organic solvents (usually acetonitrile). It has become important for the separation of pharmaceuticals, neurotransmitters, nucleosides, nucleotides and other compounds. This review presents an overview of HILIC separation systems, comparing it to several other recently described modes. (C) 2012 Elsevier Ltd. All rights reserved.
Subject: Acetonitrile
Hydrophilic interaction chromatography
Liquid chromatography
Organic solvent
Polar compound
Country: Inglaterra
Editor: Elsevier Sci Ltd
Rights: fechado
Identifier DOI: 10.1016/j.trac.2012.03.009
Date Issue: 2012
Appears in Collections:Unicamp - Artigos e Outros Documentos

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